Anabolic SteroidsThe word, steroid, has different meanings to different people. For some people, steroids are medicines they use to deal with acute conditions like arthritis, while others use it for enhancing muscle growth and performance. Steroids are most commonly linked to athletes, who are known to take them for boosting their energy levels and stamina, thereby enhancing their performance. The word, steroid, sreroids derived from two Greek words - "Stere", which means solid, and "Eidos", which means a three-dimensional form. Together, they form the word, Stereoiedes, female bodybuilding food plan means 4 types of anabolic steroids solid organic compound.
Testosterone Types and Variants
Testosterone is available in many different preparations, esterified variants, and forms. This is where each will be described and covered. Almost every single injectable anabolic steroid , with the exception of a select couple, has undergone a process known as esterification. The process of esterification refers to a chemical reaction by which a carboxylic acid of varying length is chemically bonded to the anabolic steroid at the beta hydroxyl group. This is known as esterification or an ester bond , and the ester serves to extend the release rate and half-life of the hormone in the body.
This occurs by way of enzymes breaking down the ester that is attached to the anabolic steroid. This occurs primarily in the liver, but also occurs in the bloodstream as well. The body must first break off the ester by way of the enzymes previously mentioned before the anabolic steroid hormone can be free in the body to do its job. By the time this occurs, the anabolic steroid has left the site of injection and is circulating systemically within the body.
Testosterone suspension is an un-esterified form of Testosterone, for example, as it is simply pure un-esterified Testosterone suspended in crystals in water. Pure un-esterified Testosterone possesses a very short half-life — too short, in fact, for practical application as well as inconveniently uncomfortable administration. Therefore, ester bonds of different types have been formed to create the different esterified variants of Testosterone for ease of administration and for the purpose of extending its half-life to that of more practical and useable lengths.
Adding an ester bond to the Testosterone molecule also allows the best possible maximization of use for both medical and non-medical application. Although an almost infinite amount of esterified forms and variants of Testosterone can be created or found, there exist three primary and popular types that are well-known both within medicine as well as in the anabolic steroid using community.
They are as follows in order of popularity:. In addition to these esterified variants, there also exists what are known as blends of Testosterone, which are preparations and products that contain a blend of the above mentioned esterified forms of Testosterone. For example, one of the most well-known blends is Sustanon , which contains a total of mg of Testosterone split into the following blend amounts: There exist other blend type products that contain other varying amounts, such as blends of mg of multiple Testosterone ester types, and so on and so forth.
There also exists other less popular esterified forms of Testosterone, such as Testosterone Acetate and the others contained within the Sustanon blend Testosterone Decanoate, Testosterone Phenylpropionate, Testosterone Isocaproate, etc. Testosterone Enanthate is perhaps the most popular and most widely used esterified variant of Testosterone. This is due in large part to its longer half-life and extended window of release, which allows for more convenient injection administration protocols.
Unesterified Testosterone, such as Testosterone suspension is even worse for those who are needle-shy or do not wish to engage in frequent injections due to the fact that it must be injected either more than once daily, or at the very least once daily. Because of the longer half-life, it is better suited for medical and TRT applications , but also well suited for performance enhancing use as well for those who do not wish to engage in frequent injections, as previously mentioned.
Testosterone Cypionate, although chemically different from Testosterone Enanthate, is considered almost the equivalent. It too possesses a similar half-life, although slightly longer approximately 12 days for Testosterone Cypionate and approximately 10 days for Testosterone Enanthate.
The other primary difference between the two is that of their origins — Testosterone Enanthate is primarily an international product with international origins, while Testosterone Cypionate is traditionally an American product. Both are very similar in terms of their half-lives, and hold almost equal popularity among anabolic steroid users with Testosterone Enanthate being the more popular of the two.
The two esterified Testosterone variants are in fact so similar to one another that they can be easily interchanged within a cycle for example, an individual on a 10 week Testosterone cycle could easily utilize Testosterone Enanthate for the first 5 weeks, and then for the remaining 5 weeks switch to Testosterone Cypionate with no problems what so ever.
The conveniences with Testosterone Cypionate is the same as any other long-estered compound such as Testosterone Enanthate , which is ease and convenience of more infrequent administration. Testosterone Propionate lands itself as the third most popular of the three major types of Testosterone esters despite the fact that it was the very first esterified form of Testosterone to be created.
Therefore, maintaining stable blood plasma levels of the hormone requires a significantly more frequent injection and administration protocol at least every other day injections than the other ester types, making it less popular among the majority of individuals who prefer less frequent injections. Nevertheless, this is not to say that Testosterone Propionateis an unpopular anabolic steroid — on the contrary, it is very popular and caters to a niche group of anabolic steroid users that prefer it among the others.
It just so happens to be that due to the uncomfortable and inconvenient injections and administration schedule, Testosterone Propionate is merely the least popular of the three. It is very important to understand the importance of maintaining what is known as a stable blood plasma level of the hormone so as to ensure proper optimal gains, optimal physiological function, and less incidence of side effects.
Although many anabolic steroids are esterified, which lends to an extended release and half-life of the hormone, the esterification still does not provide a completely steady stable rise and maintenance of peak blood levels. This is very important to understand in regards to proper dosing and administration scheduling, as the maintenance of proper steady and stable peak optimal blood levels of the hormone is essential to proper functioning.
Blood levels of almost any ester type will peak approximately 48 hours following injection. The difference that these esters will make is the time required to achieve a steady state blood plasma levels that are optimal, which is generally achieved over the long term with the longer esters such as Cypionate and Enanthate. Esters are, for the most part, long-chain hydrocarbons which classifies them as fats, making them lipophilic fat soluble , and thereby making whatever compound they are chemically bound to also lipophilic in this case, Testosterone.
Following an injection, the oil that contains the hormone will form what is called a depot deposit within the muscle tissue, and the hormone will slowly move away from the oil to which it is lipophilic, and into circulation in the bloodstream. It stands to reason then that the longer the hydrocarbon chain of the ester in question, the more fat soluble a hormone will be, and therefore this will contribute to the extended release of the hormone. This is the reason as to why anabolic steroids with an extremely long ester chain, such as Deca-Durabolin Nandrolone Decanoate hold such a long half-life and are known to even remain in fatty tissues in the body for months after administration has ceased.
Once the hormone has released from the injection site into bloodstream circulation, enzymes, as mentioned many times already, will work to break the ester away from the hormone.
It is very important to note to the reader that while the hormone remains bound to the ester, the anabolic steroid hormone is inactive and cannot perform any of its jobs until the ester has been removed. Considering the half-life of the various types of Testosterone esters, there are different protocols among them that must be considered in order to achieve stable blood plasma levels. There is also a difference between those individuals looking to use Testosterone for the purpose of performance and physique enhancement, and those looking to use it for the purpose of TRT.
It should be outlined very first that the use of Testosterone of any ester type for TRT allows a far more lenient and lax injection protocol than for the purpose of performance enhancement. This is because the overall goal of TRT is that of maintaining normal physiological Testosterone levels and proper normal physiological function. Therefore, an individual utilizing the following Testosterone variants for TRT should operate efficiently on the proper injection frequency protocols as outlined by medical prescription guidelines:.
Administration injection once every 2 — 4 weeks. Sustanon or any Testosterone blends TRT: Administration injection once every 3 weeks.
Often times many doctors will settle on an injection frequency with their patients of a once weekly injection for Testosterone Enanthate or Cypionate, for example. Many medical professionals have believed that the injection protocols as outlined by medical prescription guidelines require revision so as to ensure more frequent injection protocols in order to achieve more stable blood levels, but nevertheless, medical prescription guidelines remain as listed above.
For the purpose of performance and physique enhancement, the administration protocol for the different types of Testosterone esters is very different, involving a far more frequent injection protocol and scheduling. This is because specific increases in strength, size, and changes in body composition is desired with the minimized incidence of side effects, which can only be achieved with a properly attainable peak blood plasma level:.
Testosterone Enanthate performance enhancement: Administration injection twice weekly with each injection spaced evenly apart example: Monday and Thursday injections. Testosterone Cypionate performance enhancement: Testosterone Propionate performance enhancement: Administration injection once every other day. Sustanon or any Testosterone blends performance enhancement: Administration injection once every 7 — 10 days with some protocols even calling for once every 3 days.
Although the longer estered Testosterone variants such as Cypionate and Enanthate hold longer half-lives of approximately 10 — 12 days, it is imperative that for the purpose of physique and performance enhancement they are administered at least once weekly, with the optimal being twice weekly spaced evenly apart. Blended products such as Sustanon are a complex and interesting topic, as Sustanon presents disadvantages to the athlete and bodybuilder in comparison to other single Testosterone ester type has been defined several times already.
This disadvantage is due in large part to the fact that there is very little control over the varying release rates of the different Testosterone esters within the Sustanon blend. Therefore, any user willing to utilize Sustanon or any type of blended Testosterone product will find they are disposed to having far less control and management of half-lives, and proper dosing. Nevertheless, for the purpose of physique and performance enhancement, Sustanon doses must be administered approximately every 7 — 10 days instead of the medical guidelines of once every three weeks.
Some have even favored administration of Sustanon doses once every 3 days, as the reasoning behind this is that of the use of short-estered Testosterone variants in the blend.
If any product is a blended product whether it is Sustanon or any other underground lab type of custom blend , the one ester type within the blend to determine the administration protocol off of should always be: The shortest ester type if it comprises the largest concentration among all others in the blend. Testosterone is an extremely popular and very common anabolic steroid on the market, both within medicine as well as on the anabolic steroid black market across the globe.
The majority of individuals utilizing Testosterone for the purpose of physique and performance enhancement will normally elect to purchase anabolic steroids through the black market, which could result in pharmaceutical grade product as well as underground lab UGL product.
The fact is, however, the majority of Testosterone or any anabolic steroid product on the black market is in fact UGL quality. Although pharmaceutical grade products can also be purchased from the black market, the risk of fake counterfeit pharmaceutical products is extremely high.
Although the majority of UGL products are utilized by those looking to use them for performance enhancing purposes, there are also individuals who will take it upon themselves to self-administer TRT and do this through purchasing UGL grade Testosterone rather than doing this through a doctor and obtaining their Testosterone product through the pharmacy.
Regardless of the cause for use, the two types of Testosterone products that all individuals will encounter when looking to purchase is of the following two types:. These are pharmaceutical products contrived and promoted by FDA or any equivalent association approved pharmaceutical corporations. The products resultant from these corporations is of very high quality, precisely dosed, definite sterility, and purity.
This is due to the immense amount of oversight tight quality control by the FDA or any similar international organization. Underground lab UGL grade: Underground labs are laboratories that established often illegally, depending on which country to produce anabolic steroids. They are inspected, overseen, or approved by the FDA or any equivalent organization. The manufacturing conditions run by these laboratories can range from pharmaceutical grade facilities to home based laboratories established in a house basement, which would then translate to wildly varying ranges of quality in the products due to no FDA or similar oversight and quality control.
The benefit to UGL grade products is, of course, the lower cost of product in comparison to pharmaceutical grade anabolic steroids. The cost differences between pharmaceutical and UGL Testosterone can be quite strikingly different.
All products obviously depend on the lab in question that is manufacturing the product, and this must always be kept in mind. The last Testosterone variant and product to be discussed are the Testosterone creams and gels for the purpose of TRT. These are properly known as transdermal patches, gels, and creams that utilize the transdermal method of administration as opposed to the oral or injection routes of administration.
Transdermal administration is a route of administration whereby the active ingredients contained within the cream, gel, or patch will cross through the skin by entering the pores, and enter the bloodstream to enter circulation through this method.
Although there are a few advantages to transdermal methods of administration, there exist various disadvantages as well. Because TRT is a method of therapy that requires the consistent administration of Testosterone daily or weekly depending on the route of administration , there is a manner of convenience to this method of administration for individuals that do not wish to resort to injections for whichever reason they choose.
However, transdermal administration of Testoserone tends to be associated with the potential of experiencing far more disadvantages than advantages. Advantages of transdermal administration: The advantages lay mostly in convenience, as a simple topical rub on of a certain amount of the gel or cream or application of a patch daily is all that is required for administration.
Disadvantages of transdermal administration: There exist numerous concerns and disadvantages when transdermal administration of creams and gels are concerned. The first and foremost issue of concern is the problem of skin-to-skin contact with the individual who is utilizing the topical gel or cream, which can often result in the transference of Testosterone from the TRT patient to the other individual.